Description

Sodium Trifluoroacetate is the sodium salt of trifluoroacetic acid, a key organofluorine compound. It serves as a versatile reagent and building block, valued for its strong electron-withdrawing trifluoromethyl group which imparts unique chemical properties. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors, particularly for synthesis, derivatization, and as a precursor in fluorination chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl groups to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoroacetate moiety contributes to efficacy.
• Peptide Synthesis & Protection: Acts as a reagent for the introduction and removal of protecting groups (e.g., TFA salt formation) in solid-phase peptide synthesis (SPPS).
• Nucleic Acid Research: Employed in oligonucleotide synthesis and as a component in buffers for analytical techniques like HPLC and Mass Spectrometry.
• Catalyst & Ligand Precursor: Serves as a starting material for generating catalysts and ligands used in cross-coupling and other transition metal-catalyzed reactions.
• Analytical Chemistry: Used as a volatile ion-pairing agent in liquid chromatography-mass spectrometry (LC-MS) to improve separation and detection of analytes.
• Polymer & Material Science: A monomer or modifier in the synthesis of fluorinated polymers and advanced materials with specific surface properties.
• Organic Synthesis Reagent: A source of the trifluoroacetate anion for various transformations, including esterifications and as a mild base or nucleophile.

Basic Information

Item	Details
Product Name	Sodium Trifluoroacetate
CAS No.	2923-18-4
Molecular Formula	C2F3NaO2
Molecular Weight	136.01 g/mol
Synonyms	Trifluoroacetic acid sodium salt; Sodium trifluoroethanoate; TFA sodium salt; CF3COONa; Natriumtrifluoroacetat; UNII-5Q8U6F6M6Q
EINECS	220-892-1

Quality Control

Our Sodium Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture from the air, which can affect product quality and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
pH (5% solution)	6.0 - 8.0
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.