Description

Potassium Trifluoroacetate is a versatile organofluorine salt widely used as a key reagent and intermediate in advanced chemical synthesis. Its primary value lies in its ability to introduce the trifluoroacetate group, a crucial moiety for modifying the physical and chemical properties of target molecules. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty materials industries, where precise fluorination is required.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring trifluoromethyl groups to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoroacetate moiety can improve efficacy and environmental profile.
• Peptide Chemistry: Serves as a reagent for the protection and deprotection of amino acids during solid-phase peptide synthesis (SPPS).
• Organic Synthesis Reagent: Acts as a source of the trifluoroacetate anion for esterification, transesterification, and as a mild base or nucleophile in various reactions.
• Ligand and Catalyst Preparation: Employed in the preparation of metal-organic complexes and catalysts used in cross-coupling and other catalytic processes.
• Material Science: Used in the surface modification of materials and in the synthesis of fluorinated polymers and coatings with unique properties.

Basic Information

Product Name	Potassium Trifluoroacetate
CAS No.	2923-16-2
Molecular Formula	C2F3KO2
Molecular Weight	152.12 g/mol
Synonyms	Trifluoroacetic acid potassium salt; Potassium trifluoroethanoate; TFA-K; CF3COOK; Potassium perfluoroacetate; Potassium 2,2,2-trifluoroacetate
EINECS	220-882-9

Quality Control

Our Potassium Trifluoroacetate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and moisture content. Our quality commitment supports compliance with cGMP and ISO 9001 standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent caking and decomposition. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
pH (5% solution)	6.0 - 8.0
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.