Description

2,6-Dichlorobenzonitrile N-Oxide is a specialized aromatic nitrile oxide derivative, a key reactive intermediate in synthetic organic chemistry. Its primary value lies in its role as a 1,3-dipole in cycloaddition reactions, enabling the efficient construction of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals through click chemistry and other advanced synthetic methodologies.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing isoxazoline and isoxazole heterocycles, which are core structures in numerous drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific isoxazoline motifs for bioactivity.
• Material Science Research: Serves as a versatile dipolarophile in polymer and dendrimer functionalization via 1,3-dipolar cycloaddition "click" reactions.
• Chemical Biology Probes: Employed in the synthesis of bioconjugates and molecular probes for studying biological systems and target engagement.
• Fine Chemical Production: Acts as a precursor for synthesizing complex, high-value specialty chemicals used in electronics and advanced materials.

Basic Information

Product Name	2,6-Dichlorobenzonitrile N-Oxide
CAS No.	2904-62-3
Molecular Formula	C7H3Cl2NO
Molecular Weight	187.01 g/mol
Synonyms	2,6-Dichlorobenzonitrile Oxide; 2,6-Dichlorobenzonitrile N-Oxide; 2,6-Dichlorobenzonitrile 1-Oxide; Benzonitrile, 2,6-dichloro-, N-oxide; 2,6-Dichlorophenyl nitrile oxide; (2,6-Dichlorophenyl)(oxo)methanimine oxide
EINECS	220-828-6

Quality Control

Our 2,6-Dichlorobenzonitrile N-Oxide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.