Description

Cbz-n-Methyl-L-Phenylalanine is a protected amino acid derivative of significant importance in synthetic organic and medicinal chemistry. Its core value lies in serving as a versatile chiral building block for the controlled synthesis of complex peptides and peptidomimetics. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology industries, particularly for developing novel therapeutic agents and conducting advanced biochemical studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce an N-methylated phenylalanine residue, which can enhance metabolic stability and membrane permeability of peptides.
• Protease Inhibitor Development: Employed in the design and synthesis of protease inhibitors due to its modified backbone structure.
• Biochemical Research: Utilized as a substrate or building block in enzymatic studies and for probing protein-protein interactions.
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening to discover new bioactive molecules.
• Academic & Industrial R&D: Serves as a standard reagent in laboratories focused on organic synthesis, medicinal chemistry, and chemical biology.

Basic Information

Product Name	Cbz-n-Methyl-L-Phenylalanine
CAS No.	2899-07-2
Molecular Formula	C18H19NO4
Molecular Weight	313.35 g/mol
Synonyms	N-Carbobenzoxy-N-methyl-L-phenylalanine; N-[(Benzyloxy)carbonyl]-N-methyl-L-phenylalanine; Z-N-Me-Phe-OH; CBZ-N-Methyl-L-Phenylalanine; N-Cbz-N-methyl-L-phenylalanine; (2S)-2-[[(Benzyloxy)carbonyl](methyl)amino]-3-phenylpropanoic acid; Benzyl N-methyl-N-[(2S)-1-oxo-3-phenyl-1-oxopropan-2-yl]carbamate; N-Benzyloxycarbonyl-N-methyl-L-phenylalanine
EINECS	220-795-8

Quality Control

Our Cbz-n-Methyl-L-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation analysis, to ensure high chemical and chiral purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.