Description

(6S)-Bicyclo[2.2.1]Hept-2-Ene-6-Carbonitrile is a high-purity, chiral bicyclic nitrile building block of significant interest in advanced organic synthesis. Its rigid, strained bicyclic framework and functional handles make it a valuable precursor for constructing complex molecular architectures with precise stereochemistry. This compound is primarily utilized by pharmaceutical R&D and fine chemical sectors for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory applications.
• Asymmetric Catalysis Ligand Precursor: Used to develop novel chiral ligands and catalysts for enantioselective transformations in fine chemical manufacturing.
• Advanced Material Synthesis: Serves as a building block for polymers and specialty chemicals with unique thermal or mechanical properties derived from its rigid bicyclic structure.
• Agrochemical Research: Employed in the discovery and development of new, more effective crop protection agents with specific stereochemical requirements.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry, including cycloaddition reactions and functional group transformations.

Basic Information

Product Name	(6S)-Bicyclo[2.2.1]Hept-2-Ene-6-Carbonitrile
CAS No.	2890-96-2
Molecular Formula	C9H9N
Molecular Weight	131.18 g/mol
Synonyms	(1S,4R)-1,3-Dihydro-1,4-methano-1H-indene-6-carbonitrile; (6S)-6-Cyanobicyclo[2.2.1]hept-2-ene; (1S,4R)-6-Cyano-1,4-methano-1H-indene; (6S)-Bicyclo[2.2.1]hept-2-ene-6-carbonitrile; (1S,4R)-1,4-Methano-1H-indene-6-carbonitrile; (S)-6-Cyanonorbornene; (S)-Norbornene-6-carbonitrile
EINECS	Contact for details

Quality Control

Our (6S)-Bicyclo[2.2.1]Hept-2-Ene-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.