Description

L-Methioninamide, L-Alanyl-L-Phenylalanyl-L- Isoleucylglycyl-L-Methionyl-, Monohydrochloride is a high-purity synthetic peptide derivative, specifically a protected pentapeptide sequence. This compound is of significant value in advanced pharmaceutical research and development, serving as a critical building block or intermediate for the synthesis of more complex bioactive peptides and peptidomimetics. It is primarily needed by research institutions, biotechnology firms, and pharmaceutical companies engaged in drug discovery, particularly for developing therapeutic agents targeting metabolic and neurological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase or solution-phase synthesis of novel therapeutic peptides.
• Biochemical Research: Used as a standard or reference compound in proteomics and peptide structure-activity relationship (SAR) studies.
• Drug Discovery: Employed in high-throughput screening assays to identify and optimize new drug candidates with specific biological activity.
• Peptide Library Construction: A valuable component for creating combinatorial peptide libraries used to discover new bioactive sequences.
• Academic Research: Utilized in university and institutional labs for fundamental studies on peptide synthesis, folding, and receptor interaction.

Basic Information

Product Name	L-Methioninamide, L-Alanyl-L-Phenylalanyl-L- Isoleucylglycyl-L-Methionyl-, Monohydrochloride
CAS No.	2807-80-9
Molecular Formula	C31H49N7O6S2 • HCl
Molecular Weight	700.35 g/mol (free base: 663.90 g/mol)
Synonyms	H-Ala-Phe-Ile-Gly-Met-NH2 • HCl; AFIGM-NH2 • HCl; L-Alanyl-L-phenylalanyl-L-isoleucylglycyl-L-methioninamide monohydrochloride; Pentapeptide amide (Ala-Phe-Ile-Gly-Met-NH2) hydrochloride; Protected AFIGM peptide amide; 2807-80-9; Ala-Phe-Ile-Gly-Methioninamide hydrochloride
EINECS	Contact for details

Quality Control

Our L-Methioninamide, L-Alanyl-L-Phenylalanyl-L- Isoleucylglycyl-L-Methionyl-, Monohydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Anhydrous Basis)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.