Description

n-(Trifluoroacetyl)-L-Leucine Butyl Ester is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound is a critical building block in the production of peptides and fine chemicals, offering excellent reactivity and selectivity. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key protected precursor in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Bioconjugation Reagent: Used for modifying proteins, antibodies, or other biomolecules by introducing the leucine side chain with a trifluoroacetyl-protected amine.
• Organic Synthesis Building Block: Serves as a versatile chiral synthon for constructing complex natural products and specialty chemicals in research and development.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides that require specific amino acid-based structures for bioactivity.
• Proteomics & Biochemistry: Utilized in metabolic studies and as a standard or reagent in analytical methodologies involving amino acid analysis.

Basic Information

Product Name	n-(Trifluoroacetyl)-L-Leucine Butyl Ester
CAS No.	2796-38-5
Molecular Formula	C₁₂H₂₀F₃NO₃
Molecular Weight	283.29 g/mol
Synonyms	L-Leucine, N-[(trifluoroacetyl)-, butyl ester; Butyl N-(trifluoroacetyl)-L-leucinate; N-(Trifluoroacetyl)leucine butyl ester; N-TFA-L-leucine butyl ester; (S)-2-((Trifluoroacetyl)amino)-4-methylpentanoic acid butyl ester; Butyl (2S)-2-[[2,2,2-trifluoroacetyl]amino]-4-methylpentanoate; 2796-38-5; N-α-Trifluoroacetyl-L-leucine n-butyl ester
EINECS	Contact for details

Quality Control

Our n-(Trifluoroacetyl)-L-Leucine Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and production. Certificates of Analysis (COA) with full traceability are provided to guarantee consistent quality and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.