Description

Acth (1-10) CAS NO 2791-05-1 is a synthetic peptide fragment corresponding to the first ten amino acids of the adrenocorticotropic hormone (ACTH). This compound is a critical research tool for studying the structure-activity relationships of ACTH and its role in the hypothalamic-pituitary-adrenal axis. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biochemical manufacturers. Its defined structure allows for precise investigations into peptide signaling and potential therapeutic applications.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of ACTH receptor binding, steroidogenesis, and peptide hormone function.
• Pharmaceutical Development: Serves as a key intermediate or lead compound in the design and synthesis of novel peptide-based therapeutics targeting metabolic and endocrine disorders.
• Diagnostic Reagent Manufacturing: Employed in the production of calibration standards and components for immunoassay kits measuring ACTH-related pathways.
• Neuroscience Studies: Applied in research exploring the effects of ACTH fragments on behavior, learning, and neural function.
• Academic & Institutional Laboratories: A fundamental reagent for teaching and advanced research in endocrinology, peptide chemistry, and molecular biology.

Basic Information

Product Name	Acth (1-10)
CAS No.	2791-05-1
Molecular Formula	C₅₆H₈₃N₁₇O₁₆S
Molecular Weight	1306.5 g/mol
Synonyms	ACTH (1-10); Adrenocorticotropic Hormone (1-10); Corticotropin (1-10); Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly; H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-OH; ACTH Fragment 1-10; Synacthen fragment (1-10); Cosyntropin fragment (1-10)
EINECS	Contact for details

Quality Control

Every batch of Acth (1-10) is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for research and development purposes. A Certificate of Analysis (COA) detailing purity (by HPLC), amino acid analysis, and mass spectrometry confirmation is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.