Description

Z-Val-Gly-Oh is a protected dipeptide building block, specifically the C-terminal carboxylic acid of Z-Val-Gly. This compound is a crucial intermediate in the synthesis of more complex peptides and peptidomimetics, offering controlled coupling and deprotection steps. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry and drug discovery. Its defined structure ensures reproducibility and high purity in synthetic pathways.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of peptide chains on resin.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for constructing specific peptide sequences.
• Pharmaceutical Research: Serves as a building block for the development of novel therapeutic peptides and protease inhibitors.
• Bioconjugation: Can be utilized to introduce the Val-Gly moiety into larger molecules or carrier systems.
• Chemical Biology Probes: Acts as a precursor for labeled or modified peptides used in biochemical assays.
• Reference Standard: Employed as a high-purity standard for analytical method development and quality control in peptide production.

Basic Information

Product Name	Z-Val-Gly-Oh
CAS No.	2790-84-3
Molecular Formula	C15H20N2O5
Molecular Weight	308.33 g/mol
Synonyms	N-Carbobenzoxy-L-valylglycine; N-Cbz-L-valylglycine; Z-L-Val-Gly-OH; Z-Val-Gly; Benzyloxycarbonyl-L-valylglycine; (S)-2-(((Benzyloxy)carbonyl)amino)-3-methyl-N-(2-oxo-2-(oxy)ethyl)butanamide; Cbz-Val-Gly-OH; Nα-Cbz-L-valylglycine
EINECS	220-529-3

Quality Control

Our Z-Val-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (IR, NMR). We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Optical Rotation [α]D20	-15° to -20° (c=1 in DMF)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.