Description

Glycylglycine Methyl Ester Hydrochloride is a protected dipeptide derivative essential for advanced peptide synthesis and biochemical research. This compound serves as a crucial building block, offering a reactive ester group for efficient coupling while its amino terminus is protected, enabling controlled chain elongation. It is primarily utilized by pharmaceutical R&D teams, peptide manufacturers, and academic laboratories engaged in developing novel therapeutic agents, enzyme substrates, and complex biomolecules. Its high purity and consistent quality are critical for ensuring reproducibility in sensitive synthetic workflows.

Application

• Pharmaceutical Intermediate: Key building block in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a substrate or precursor in enzymatic studies and for investigating peptide structure-activity relationships (SAR).
• Proteomics & Diagnostics: Employed in the development of labeled peptides for mass spectrometry standards and diagnostic assay components.
• Organic Synthesis: A versatile reagent for introducing the glycylglycine moiety into more complex molecular architectures.
• Cosmetic Peptides: Potential raw material in the synthesis of bioactive peptides for advanced skincare formulations.

Basic Information

Product Name	Glycylglycine Methyl Ester Hydrochloride
CAS No.	2776-60-5
Molecular Formula	C6H13N2O3 • HCl
Molecular Weight	212.64 g/mol
Synonyms	H-Gly-Gly-OMe • HCl; Gly-Gly Methyl Ester Hydrochloride; Methyl N-(2-Aminoacetyl)glycinate Hydrochloride; Glycylglycine Methyl Ester HCl; 2-[(2-Aminoacetyl)amino]acetic Acid Methyl Ester Hydrochloride; Diglycine Methyl Ester Hydrochloride; N-Glycylglycine Methyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our Glycylglycine Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent controls for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.