Description

Fluphenazine o-Enantate is a long-acting ester derivative of the potent antipsychotic agent fluphenazine. This compound is specifically engineered for sustained-release depot formulations, providing a critical solution for long-term therapeutic management. It is primarily utilized by the pharmaceutical industry for the development of injectable antipsychotic medications, offering improved patient compliance and stable plasma levels in the treatment of chronic psychiatric conditions.

Application

• Active Pharmaceutical Ingredient (API) in long-acting injectable (LAI) antipsychotic formulations.
• Key intermediate for the synthesis of advanced, sustained-release neuropsychiatric drugs.
• Research chemical in pharmacological studies focusing on dopamine receptor antagonism and pharmacokinetics.
• Development material for novel drug delivery systems, including microspheres and implants.
• Reference standard in quality control laboratories for analytical method development and validation.
• Manufacturing of depot injections for the treatment of schizophrenia and other psychotic disorders.

Basic Information

Product Name	Fluphenazine o-Enantate
CAS No.	2746-81-8
Molecular Formula	C₃₂H₄₄F₃N₃O₂S
Molecular Weight	591.77 g/mol
Synonyms	Fluphenazine Enanthate; Fluphenazine Heptanoate; Fluphenazine Enantate; 4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol heptanoate ester; Prolixin Enanthate; Dapotum D; Lyogen Depot; Anatensol Enanthate; Flufenazin enantas
EINECS	220-403-6

Quality Control

Our Fluphenazine o-Enantate is manufactured under strict quality systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical development and manufacturing. We provide comprehensive Certificates of Analysis (COA) that include data for identity, purity, and related substances, aligning with ICH guidelines. Compliance with relevant pharmacopeial standards (e.g., USP, EP) can be supported upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) to minimize oxidation. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.