Description

Acetamide, 2,2,2-Trifluoro-n-(2-Nitrophenyl)- is a specialized fluorinated aromatic amide compound with the CAS number 2727-72-2. This chemical serves as a valuable advanced intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those requiring a trifluoroacetamide and nitroaromatic pharmacophore.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides where the specific fluorine and nitro substitutions confer unique biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for further functionalization, including reduction of the nitro group or hydrolysis of the amide bond.
• Material Science Research: Potential intermediate in the development of specialty polymers, liquid crystals, or organic electronic materials due to its aromatic and polar structure.
• Chemical Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related compounds.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(2-Nitrophenyl)-
CAS No.	2727-72-2
Molecular Formula	C8H5F3N2O3
Molecular Weight	234.13 g/mol
Synonyms	2,2,2-Trifluoro-N-(2-nitrophenyl)acetamide; N-(2-Nitrophenyl)-2,2,2-trifluoroacetamide; 2-Nitroanilino-2,2,2-trifluoroacetophenone; α,α,α-Trifluoro-2'-nitroacetanilide; 2,2,2-Trifluoroacet-2'-nitroanilide; TFNA; 2-Nitrophenyltrifluoroacetamide
EINECS	Contact for details

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-(2-Nitrophenyl)- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a synthesis intermediate. Standard testing includes identification, assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.