Description

Acetamide, 2,2,2-Trifluoro-n-(3-Methylphenyl)- is a specialized fluorinated acetamide derivative, a key intermediate in advanced organic synthesis. Its molecular structure, featuring a trifluoroacetamide group linked to a meta-substituted toluene ring, provides unique reactivity and stability for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethylated aromatic amide moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced materials with specific thermal or chemical resistance properties.
• Liquid Crystal & OLED Materials: A potential intermediate in the synthesis of fluorinated compounds for electronic display and lighting applications.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex organic molecules, leveraging its amide and aryl halide functionalities for further derivatization.

Basic Information

Item	Details
Product Name	Acetamide, 2,2,2-Trifluoro-n-(3-Methylphenyl)-
CAS No.	2727-69-7
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	N-(3-Methylphenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-m-tolylacetamide; m-Tolyltrifluoroacetamide; α,α,α-Trifluoro-m-toluidide; 3-Methylphenyltrifluoroacetamide; Trifluoroacetanilide, 3'-methyl-; TFA-m-toluidide; N-(m-Tolyl)trifluoroacetamide
EINECS	220-341-5

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-(3-Methylphenyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.