Description

Lithium n-Butoxide is a versatile metal alkoxide compound, widely recognized for its strong basicity and utility as a catalyst and reagent in organic synthesis. Its primary value lies in its ability to facilitate a range of condensation and deprotonation reactions under mild conditions, offering high selectivity and yield. This makes it an essential material for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking efficient synthetic pathways.

Application

• Catalyst in Organic Synthesis: Employed as a strong base catalyst in aldol condensations, Claisen condensations, and other carbon-carbon bond-forming reactions.
• Precursor for Thin Films: Used in sol-gel processes and chemical vapor deposition (CVD) for the production of lithium-containing oxide thin films in electronic and optical applications.
• Polymerization Initiator: Acts as an anionic initiator for the polymerization of certain monomers, such as methacrylates and epoxides.
• Pharmaceutical Intermediate: A key reagent in the synthesis of complex drug molecules, particularly in steps requiring selective deprotonation or alkoxide-mediated coupling.
• Cross-Coupling Reactions: Utilized as a base in transition metal-catalyzed cross-coupling reactions, such as Suzuki and Negishi couplings.
• Esterification and Transesterification: Facilitates ester synthesis and exchange reactions under mild conditions.

Basic Information

Product Name	Lithium n-Butoxide
CAS No.	2698-11-5
Molecular Formula	C4H9LiO
Molecular Weight	80.06 g/mol
Synonyms	Lithium butoxide; Butyl lithium oxide; n-Butyl lithium oxide; Lithium tert-butoxide (Note: this is a different isomer); Lithium butylate; Lithium(1+) butan-1-olate; LiOBu
EINECS	220-267-4

Quality Control

Our Lithium n-Butoxide is manufactured under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including assay by titration and identification by FT-IR, to ensure it meets high-purity standards suitable for research and industrial applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or lumps
Identification (IR)	Conforms
Assay (LiOBu)	≥ 95.0 %
Lithium (Li) Content	Contact for details
Solubility (in Toluene)	Clear solution
Loss on Drying	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.