Description

2-[[(2-Ethylphenyl)(2-Hydroxyethyl)Amino]Methyl]-3,3-Difluoro-Propanenitrile is a specialized organic intermediate featuring a unique molecular architecture combining an aromatic ethylphenyl group, a hydroxyethylamino linker, and a difluoropropanenitrile moiety. This compound matters for its role as a key building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure imparts specific electronic and steric properties. Industries that require high-precision chemical synthesis, such as pharmaceutical development, agrochemical research, and functional material science, are the primary users of this nitrile derivative.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the difluoro and nitrile groups can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Acts as a building block for creating fluorinated organic semiconductors and liquid crystal compounds for display technologies.
• Polymer Modification: Employed to introduce functional amine and nitrile groups into polymer chains, modifying properties like adhesion, solubility, and thermal stability.
• Ligand Synthesis for Catalysis: Utilized in the preparation of complex ligands for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.
• Chemical Research & Development: Provides a versatile scaffold for medicinal chemistry and material science exploration in R&D laboratories.

Basic Information

Product Name	2-[[(2-Ethylphenyl)(2-Hydroxyethyl)Amino]Methyl]-3,3-Difluoro-Propanenitrile
CAS No.	2647-14-5
Molecular Formula	C14H18F2N2O
Molecular Weight	268.31 g/mol
Synonyms	3,3-Difluoro-2-[[(2-ethylphenyl)(2-hydroxyethyl)amino]methyl]propanenitrile; 2-[(2-Ethylphenyl)(2-hydroxyethyl)aminomethyl]-3,3-difluoropropionitrile; N-(2-Hydroxyethyl)-N-(2-ethylbenzyl)amino-3,3-difluoropropionitrile; 2647-14-5; Propanenitrile, 2-[[(2-ethylphenyl)(2-hydroxyethyl)amino]methyl]-3,3-difluoro-; Difluoro Nitrile Amino Alcohol Derivative
EINECS	Contact for details

Quality Control

Every batch of 2-[[(2-Ethylphenyl)(2-Hydroxyethyl)Amino]Methyl]-3,3-Difluoro-Propanenitrile is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We can support development projects requiring adherence to cGMP or ISO guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.