Description

3-(1,2,3,4-Tetrahydronaphthalen-6-Yl)-3-Oxopropanenitrile, also known as 3-(5,6,7,8-Tetrahydro-2-Naphthyl)-3-Oxopropionitrile, is a versatile and high-value organic intermediate characterized by its tetralin-derived ketonitrile structure. This compound matters for its role as a critical building block in the synthesis of complex molecules, offering a unique scaffold for pharmaceutical and advanced material research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used as a building block for developing new active ingredients in crop protection and pest control formulations.
• Organic Synthesis & Research: Serves as a versatile starting material for academic and industrial research in organic chemistry, enabling the construction of complex polycyclic frameworks.
• Material Science: Potential intermediate for the development of specialty polymers, liquid crystals, or organic electronic materials due to its rigid, aromatic-containing structure.
• Chemical Development: Employed in process chemistry for scale-up and optimization of synthetic routes requiring its specific molecular architecture.

Basic Information

Product Name	3-(1,2,3,4-Tetrahydronaphthalen-6-Yl)-3-Oxopropanenitrile / 3-(5,6,7,8-Tetrahydro-2-Naphthyl)-3-Oxopropionitrile
CAS No.	2623-25-8
Molecular Formula	C₁₃H₁₃NO
Molecular Weight	199.25 g/mol
Synonyms	3-Oxo-3-(5,6,7,8-tetrahydro-2-naphthyl)propanenitrile; 3-(5,6,7,8-Tetrahydro-2-naphthoyl)acetonitrile; 2-(5,6,7,8-Tetrahydro-2-naphthoyl)acetonitrile; 3-(1,2,3,4-Tetrahydro-6-naphthoyl)acetonitrile; 6-Acetyl-1,2,3,4-tetrahydronaphthalene-1-carbonitrile; β-Oxo-5,6,7,8-tetrahydro-2-naphthalenepropanenitrile; Tetralone-6-acetonitrile; Ketonitrile intermediate 2623-25-8
EINECS	Contact for details

Quality Control

Our 3-(1,2,3,4-Tetrahydronaphthalen-6-Yl)-3-Oxopropanenitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance for your synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key specifications such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.