Description

Prajmalium Bitartrate is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) derived from the Rauwolfia alkaloid class. This compound is critical for its potent antiarrhythmic and antihypertensive properties, serving as a key building block in advanced cardiovascular therapies. It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the development and production of specialized cardiac medications.

Application

• Pharmaceutical API Synthesis: Primary use as an active ingredient in the formulation of antiarrhythmic drugs for treating cardiac rhythm disorders.
• Cardiovascular Research: A vital reference standard and biochemical tool in pharmacological studies targeting ion channels and heart muscle function.
• Fine Chemical Intermediate: Serves as a precursor for the synthesis of more complex, derivative alkaloids with enhanced therapeutic profiles.
• Generic Drug Manufacturing: Essential for producing cost-effective generic versions of established antiarrhythmic medications.
• Clinical Trial Materials: Supplied as a GMP-grade compound for use in preclinical and clinical development phases of new cardiovascular drugs.
• Biochemical Assays: Used in in vitro testing to study drug-receptor interactions and cardiac cell electrophysiology.

Basic Information

Product Name	Prajmalium Bitartrate
CAS No.	2589-47-1
Molecular Formula	C27H34N2O4 • C4H6O6
Molecular Weight	634.71 g/mol
Synonyms	Prajmaline Bitartrate; N-Propylajmalinium Hydrogen Tartrate; 17-Monochloroacetylajmaline Bitartrate; NPAB; Ajmaline, 17-(chloroacetyl)-, hydrogen tartrate; Prajmaline (Bitartrate); GT-1012; R 671
EINECS	219-984-8

Quality Control

Our Prajmalium Bitartrate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification via IR and NMR spectroscopy, to ensure it meets stringent pharmaceutical standards. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.