Description

Tutin CAS NO 2571-22-4 is a potent neurotoxic sesquiterpene lactone, a natural product of significant interest in biochemical and pharmacological research. Its primary value lies in its specific biological activity, making it a crucial reference standard and investigative tool. This compound is essential for researchers and developers in the fields of toxicology, neuroscience, and natural product chemistry, where precise, high-purity materials are required for analytical and experimental work.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating neurotoxicity, sodium channel modulation, and the mechanisms of plant-derived toxins.
• Toxicology and Safety Assessment: Serves as a critical analytical standard for the detection and quantification of tutin in environmental, food safety, and forensic samples, particularly related to honey poisoning.
• Neuroscience Studies: Employed in experimental models to study convulsant activity and its effects on the central nervous system, aiding in the understanding of seizure pathways.
• Natural Product Isolation & Analysis: Acts as a key marker compound for the chemical profiling and quality control of plants in the Coriaria genus.
• Biochemical Reagent: Utilized in specialized biochemical assays to probe specific receptor or ion channel interactions due to its well-defined mechanism of action.
• Reference Material Manufacturing: Supplied to certified reference material (CRM) producers for the creation of accredited standards used in analytical laboratories worldwide.

Basic Information

Product Name	Tutin
CAS No.	2571-22-4
Molecular Formula	C15H18O6
Molecular Weight	294.30 g/mol
Synonyms	Tutin; Coriamyrtin; Dihydrotutin; 2,6,10,10-Tetramethyltricyclo[7.2.1.01,6]dodec-5-ene-3,4,11-trione; Coriaria lactone; Tutin (neurotoxin); 3,4,11-Trioxotut-5-ene
EINECS	219-919-9

Quality Control

Our Tutin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity confirmation and identity verification by spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.