Description

(±)-2-Amino-3-(3,4-Dimethoxyphenyl)-2-Methylpropiononitrile is a specialized chiral nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both amino and nitrile functional groups on a substituted phenylpropane backbone, makes it a versatile precursor for constructing complex pharmacologically active molecules. This high-purity intermediate is primarily sought by research institutions and pharmaceutical development teams engaged in the synthesis of novel compounds, particularly within the central nervous system (CNS) and cardiovascular therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of potential drug candidates, especially for neurological and cardiovascular applications.
• Asymmetric Synthesis: Utilized as a building block for creating enantiomerically pure compounds due to its chiral center, aiding in the study of structure-activity relationships (SAR).
• Medicinal Chemistry Research: Serves as a core structure for modifying and optimizing lead compounds in early-stage drug discovery programs.
• Chemical Reference Standard: Used as an analytical standard in quality control and method development for related pharmaceutical processes.
• Academic & Industrial R&D: Employed in synthetic methodology development and as a teaching tool for advanced organic chemistry involving amino nitrile chemistry.

Basic Information

Product Name	(±)-2-Amino-3-(3,4-Dimethoxyphenyl)-2-Methylpropiononitrile
CAS No.	2543-46-6
Molecular Formula	C₁₂H₁₆N₂O₂
Molecular Weight	220.27 g/mol
Synonyms	2-Amino-3-(3,4-dimethoxyphenyl)-2-methylpropiononitrile; α-Amino-3,4-dimethoxyphenylpropiononitrile; 3,4-Dimethoxy-α-(aminomethyl)benzeneacetonitrile; 2-Methyl-2-amino-3-(3,4-dimethoxyphenyl)propionitrile; DL-2-Amino-3-(3,4-dimethoxyphenyl)-2-methylpropionitrile; Amino Dimethoxyphenyl Methylpropiononitrile
EINECS	Contact for details

Quality Control

We supply (±)-2-Amino-3-(3,4-Dimethoxyphenyl)-2-Methylpropiononitrile with a focus on high chemical purity and batch-to-batch consistency, critical for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.