Description

Azetidine-2-Carboxylic Acid CAS NO 2517-04-6 is a non-proteinogenic amino acid featuring a unique four-membered azetidine ring, making it a valuable proline analog and versatile building block in organic synthesis. Its constrained ring structure is critical for modulating peptide conformation and biological activity, offering significant advantages in drug discovery and biochemical research. This high-purity intermediate is essential for pharmaceutical R&D, agrochemical synthesis, and advanced material science applications where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly protease inhibitors and other bioactive molecules.
• Peptidomimetics & Conformational Studies: Used to introduce structural constraints into peptides to study structure-activity relationships (SAR) and enhance metabolic stability.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators with improved efficacy.
• Biochemical Probe Development: Employed in the design of enzyme inhibitors and receptor ligands to investigate biological pathways.
• Material Science: A monomer or cross-linking agent for synthesizing specialized polymers with unique thermal and mechanical properties.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Azetidine-2-Carboxylic Acid
CAS No.	2517-04-6
Molecular Formula	C4H7NO2
Molecular Weight	101.10 g/mol
Synonyms	L-Azetidine-2-carboxylic acid; (S)-Azetidine-2-carboxylic acid; 2-Azetidinecarboxylic acid; Azetidinecarboxylic acid; Azetidine-2-carboxylic acid; 3-Azetidinecarboxylic acid (ambiguous); 1-Azetidinecarboxylic acid (ambiguous); Proline analog
EINECS	219-746-5

Quality Control

Our Azetidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.