Description

18-Deoxyaldosterone is a significant steroid derivative and a key intermediate in the synthesis of various mineralocorticoids and related pharmaceutical compounds. Its precise molecular structure makes it an invaluable building block for research and development in endocrinology and synthetic chemistry. This high-purity intermediate is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions focused on steroid hormone pathways and drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of aldosterone analogs and other potent mineralocorticoid receptor modulators.
• Biochemical Research: Used as a reference standard or tool compound in studies investigating the biosynthesis, metabolism, and structure-activity relationships of adrenal steroids.
• Drug Discovery & Development: Employed in medicinal chemistry programs aimed at developing novel therapeutics for conditions related to electrolyte balance and hypertension.
• Academic Research: Facilitates studies in university and institutional labs exploring steroidogenesis and hormone receptor function.
• Contract Synthesis: Supplied to CROs and CMOs for custom synthesis projects requiring high-purity steroid intermediates.

Basic Information

Product Name	18-Deoxyaldosterone
CAS No.	2507-88-2
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	18-Deoxyaldosterone; 11β,21-Dihydroxy-3,20-dioxopregn-4-en-18-al; 18-Oxo-11β,21-dihydroxypregn-4-ene-3,20-dione; Aldosterone 18-deoxy derivative; 18-Noraldosterone; Pregn-4-ene-3,20-dione, 11,21-dihydroxy-18-oxo-, (11β)-; 18-Deoxy-aldosterone
EINECS	Contact for details

Quality Control

Our 18-Deoxyaldosterone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and pharmaceutical intermediate applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.