Description

Sodium 2-(3-Amino-2,4,6-Triiodobenzyl)Butyrate is a specialized iodinated organic compound with the CAS number 2497-78-1. This compound is a critical intermediate in the synthesis of advanced X-ray contrast media, valued for its high iodine content and water-soluble sodium salt form. It is primarily required by pharmaceutical manufacturers and research institutions developing next-generation diagnostic imaging agents. The product's consistent quality and purity are paramount for ensuring the safety and efficacy of the final pharmaceutical formulations.

Application

• Key Intermediate for X-ray Contrast Media: Primary building block in the synthesis of non-ionic, low-osmolar contrast agents for computed tomography (CT) and angiography.
• Pharmaceutical Research & Development: Used in the discovery and development of novel iodinated compounds for diagnostic imaging.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes to final API molecules like iopamidol, iohexol, or ioversol analogs.
• Biomedical Research: Employed in studies investigating radiopaque agents and their biodistribution.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in contrast media production.

Basic Information

Product Name	Sodium 2-(3-Amino-2,4,6-Triiodobenzyl)Butyrate
CAS No.	2497-78-1
Molecular Formula	C11H11I3NNaO2
Molecular Weight	648.92 g/mol
Synonyms	2-(3-Amino-2,4,6-triiodobenzyl)butyric acid sodium salt; Sodium 3-Amino-2,4,6-triiodohydrocinnamate derivative; Butyric acid, 2-[(3-amino-2,4,6-triiodophenyl)methyl]-, sodium salt; ATBC Sodium Salt; Iodinated benzylbutyrate sodium salt; Sodium α-(3-Amino-2,4,6-triiodobenzyl)butyrate; 2497-78-1; NSC 113994
EINECS	Contact for details

Quality Control

Our Sodium 2-(3-Amino-2,4,6-Triiodobenzyl)Butyrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.