Description

n-(Benzyloxycarbonyl)-L-Alanine Benzylamide is a protected amino acid derivative widely used as a key chiral building block in organic synthesis. This compound is essential for the controlled formation of peptide bonds, enabling the production of complex molecules with high stereochemical purity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the development of active pharmaceutical ingredients (APIs), peptide hormones, and other biologically active compounds.

Application

• Peptide Synthesis: A crucial intermediate in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled incorporation of L-alanine.
• Pharmaceutical Research: Serves as a protected amino acid precursor in the R&D of novel therapeutic peptides and peptidomimetics.
• API Manufacturing: Used in the scalable production of Active Pharmaceutical Ingredients (APIs) requiring specific chiral centers.
• Bioconjugation: Employed in the synthesis of peptide-based linkers and carriers for drug delivery systems.
• Fine Chemical Production: Acts as a chiral synthon for creating complex organic molecules in asymmetric synthesis.
• Biochemical Research: Utilized in studies of enzyme-substrate interactions and protein structure-activity relationships.

Basic Information

Product Name	n-(Benzyloxycarbonyl)-L-Alanine Benzylamide
CAS No.	2489-19-2
Molecular Formula	C18H20N2O3
Molecular Weight	312.36 g/mol
Synonyms	Z-L-Ala-NH-Bzl; Cbz-L-Alanine Benzylamide; N-Carbobenzoxy-L-alanine Benzylamide; Nα-Cbz-L-alaninamide N-benzyl; Benzyl N-[(benzylamino)carbonyl]-L-alaninate; (S)-2-(((Benzyloxy)carbonyl)amino)-N-benzylpropanamide; N-Cbz-L-Ala-Bzl; L-Alanine, N-[(phenylmethoxy)carbonyl]-, N-(phenylmethyl)amide
EINECS	219-643-6

Quality Control

Our n-(Benzyloxycarbonyl)-L-Alanine Benzylamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Melting Point	118 - 122 °C
Loss on Drying	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.