Description

Cbz-L-Thr-L-Ala-Ome CAS NO 2483-53-6 is a protected dipeptide derivative, specifically the methyl ester of the Cbz-protected L-Threonyl-L-Alanine sequence. This compound serves as a crucial building block (synthon) in the synthesis of more complex peptides and peptidomimetics, offering precise control over stereochemistry and side-chain functionality. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in drug discovery, process development, and the production of specialized bioactive compounds.

Application

• Pharmaceutical Intermediate: Key raw material in the solid-phase and solution-phase synthesis of therapeutic peptides targeting various diseases.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, structure-activity relationship (SAR) investigations, and proteomics research.
• Peptidomimetic Development: Serves as a scaffold for creating modified peptide analogs with enhanced stability, bioavailability, or receptor affinity.
• Custom Peptide Synthesis: Essential building block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptide sequences for clients.
• Academic Research: Employed in university and institutional labs for methodological development in organic and medicinal chemistry.
• Reference Standard: Can be used as a high-purity chromatographic or spectroscopic standard for quality control in peptide production.

Basic Information

Product Name	Cbz-L-Thr-L-Ala-Ome
CAS No.	2483-53-6
Molecular Formula	C16H22N2O6
Molecular Weight	338.36 g/mol
Synonyms	N-Carbobenzoxy-L-threonyl-L-alanine methyl ester; Z-L-Thr-L-Ala-OMe; N-(Benzyloxycarbonyl)-L-threonyl-L-alanine methyl ester; (2S,3R)-2-[[(2S)-2-(Methoxycarbonyl)ethyl]amino]-3-[[(phenylmethoxy)carbonyl]amino]-4-oxobutanoic acid; CBZ-Thr-Ala-OMe; Z-Thr-Ala-OMe; Benzyl N-[(2S,3R)-1-[[(2S)-1-methoxy-1-oxopropan-2-yl]amino]-3-[[(phenylmethoxy)carbonyl]amino]-1-oxobutan-2-yl]carbamate; Nα-Cbz-L-threonyl-L-alanine methyl ester
EINECS	Contact for details

Quality Control

Our Cbz-L-Thr-L-Ala-Ome is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.