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Boc-Lys(For)-Oh CAS NO 2483-47-8
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CAS No.:2483-47-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Boc-Lys(For)-OH is a protected amino acid derivative, specifically Nε-Boc-Nα-formyl-L-lysine, widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise control over lysine side-chain reactivity during solid-phase and solution-phase peptide assembly. It is primarily utilized by the pharmaceutical, biotechnology, and life sciences industries for the development of novel therapeutic peptides, research biochemicals, and complex organic molecules.
Application
- Peptide Synthesis: A key intermediate for the controlled incorporation of lysine residues, protecting the Nε-amine with the Boc group and the Nα-amine with the formyl group.
- Pharmaceutical Research: Used in the research and development of peptide-based drugs, including hormone analogs, antimicrobial peptides, and targeted therapeutics.
- Bioconjugation: Serves as a precursor for creating functionalized lysine derivatives used in antibody-drug conjugates (ADCs) and protein labeling.
- Combinatorial Chemistry: Employed in the generation of peptide libraries for high-throughput screening and drug discovery programs.
- Biochemical Tool Development: Integral for synthesizing custom peptides used as enzyme substrates, inhibitors, or standards in diagnostic assays.
- Academic Research: A fundamental reagent in university and institutional labs for studying protein structure-function relationships and synthetic methodology.
Basic Information
| Product Name | Boc-Lys(For)-OH |
| CAS No. | 2483-47-8 |
| Molecular Formula | C13H24N2O5 |
| Molecular Weight | 288.34 g/mol |
| Synonyms | Nε-Boc-Nα-Formyl-L-lysine; Nα-Formyl-Nε-(tert-butoxycarbonyl)-L-lysine; (S)-2-Formylamino-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid; Boc-Lys(Nα-For)-OH; Fmoc-Lys(Boc)-OH precursor; Boc-Lys(For); N-Formyl-N'-Boc-L-lysine |
| EINECS | Contact for details |
Quality Control
Our Boc-Lys(For)-OH is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible performance and supply chain traceability.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥98.0% |
| Optical Rotation [α]D20 | +15.0° to +18.0° (c=1 in DMF) |
| Chiral Purity (HPLC) | ≥99.0% L-isomer |
| Water Content (KF) | ≤0.5% |
| Heavy Metals | ≤10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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