Description

6-Iodo-1-Hexyne is a versatile alkyne building block featuring a terminal iodine atom, making it a valuable reagent for cross-coupling reactions and organic synthesis. Its structure enables efficient carbon-carbon bond formation, which is critical for constructing complex molecular architectures in advanced research and development. This compound is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing active ingredients and novel functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via Sonogashira and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators requiring alkyne functionalization.
• Material Science & Polymer Chemistry: Acts as a monomer or functionalization agent in the creation of conductive polymers, dendrimers, and other advanced materials with tailored properties.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Bioconjugation: Utilized as a click chemistry component (e.g., in copper-catalyzed azide-alkyne cycloaddition) for labeling biomolecules and developing probes.
• Organic Synthesis Building Block: Fundamental reagent for constructing complex natural products and organic molecules in academic and industrial R&D laboratories.

Basic Information

Product Name	6-Iodo-1-Hexyne
CAS No.	2468-56-6
Molecular Formula	C6H9I
Molecular Weight	208.04 g/mol
Synonyms	1-Hexyne, 6-iodo-; 6-Iodohex-1-yne; Iodohex-1-yne; 1-Iodo-5-hexyne; 5-Hexyn-1-yl iodide; 6-Iodohex-1-yne; Hex-1-yn-6-yl iodide
EINECS	219-567-9

Quality Control

Our 6-Iodo-1-Hexyne is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and industrial applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by GC/HPLC), identity confirmation, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.