Description

L-Leucine Benzyl Ester Hydrochloride is a protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the controlled construction of complex peptides and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents and fine chemical intermediates.

Application

• Peptide Synthesis: A key intermediate in solid-phase and solution-phase peptide synthesis for constructing specific amino acid sequences.
• Pharmaceutical Research: Used as a chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs) and prodrugs.
• Biochemical Studies: Employed in enzymatic studies and as a substrate analog to investigate metabolic pathways.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialized fine chemicals, flavors, and fragrances.
• Academic Research: A valuable reagent in university and institutional labs for synthetic organic chemistry projects and methodology development.

Basic Information

Product Name	L-Leucine Benzyl Ester Hydrochloride
CAS No.	2462-35-3
Molecular Formula	C₁₃H₂₀ClNO₂
Molecular Weight	257.76 g/mol
Synonyms	L-Leucine benzyl ester hydrochloride; (S)-2-Amino-4-methylpentanoic acid benzyl ester hydrochloride; H-Leu-OBzl·HCl; Benzyl L-leucinate hydrochloride; Leucine benzyl ester HCl; L-Leucine, benzyl ester, hydrochloride; (S)-Benzyl 2-amino-4-methylpentanoate hydrochloride; Leucine benzyl ester monohydrochloride
EINECS	219-554-4

Quality Control

Our L-Leucine Benzyl Ester Hydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	+15.0° to +18.0° (c=1 in methanol)
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.