Description

Pipamperone Dihydrochloride is a high-purity pharmaceutical intermediate and reference standard of significant importance in neuropharmacological research and development. Its primary value lies in its role as the active salt form of Pipamperone, a butyrophenone derivative with established pharmacological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and life science sectors, particularly those focused on central nervous system (CNS) agents, analytical method development, and quality control.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments (HPLC, GC-MS) and the validation of testing methods in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the synthesis of finished dosage forms for neuroleptic medications.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate dopamine receptor antagonism and related neurological pathways.
• Metabolite Studies: Utilized as a standard in pharmacokinetic and metabolic profiling to understand drug disposition.
• Impurity Profiling: Acts as a known impurity or degradation product standard in the stability testing of related pharmaceutical compounds.
• Contract Manufacturing & Development (CMO/CDMO): Supplied to organizations engaged in the custom synthesis and scale-up of specialty neuropharmaceuticals.

Basic Information

Product Name	Pipamperone Dihydrochloride
CAS No.	2448-68-2
Molecular Formula	C21H30FN3O·2HCl
Molecular Weight	440.40 g/mol
Synonyms	Pipamperone 2HCl; 1′-[4-(4-Fluorophenyl)-4-oxobutyl]-[1,4′-bipiperidine]-4′-carboxamide dihydrochloride; Floropipamide dihydrochloride; Dipiperon dihydrochloride; Piperonylpiperazine dihydrochloride; MCN-JR-6234; EINECS 219-492-3
EINECS	219-492-3

Quality Control

Our Pipamperone Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.