Description

H-Gly-Pro-Gly-OH is a synthetic tripeptide composed of glycine and proline residues. This compound is a valuable building block in peptide synthesis and biochemical research, offering a defined sequence for studying structure-activity relationships. It is particularly relevant for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require high-purity peptide intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the solid-phase or solution-phase synthesis of longer, more complex therapeutic peptides.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, particularly those involving proteases like dipeptidyl peptidase, to investigate cleavage specificity and kinetics.
• Structure-Activity Relationship (SAR) Studies: Provides a defined tripeptide sequence for modeling and understanding the impact of the Gly-Pro motif on peptide conformation and biological activity.
• Cosmetic Peptide Synthesis: Can be incorporated into the synthesis of bioactive peptides for cosmetic applications, such as collagen synthesis stimulators or anti-aging compounds.
• Academic & Industrial R&D: Employed in laboratories for method development, calibration, and as a reference material in chromatographic analysis (HPLC, LC-MS).

Basic Information

Product Name	H-Gly-Pro-Gly-OH
CAS No.	2441-63-6
Molecular Formula	C10H16N4O4
Molecular Weight	256.26 g/mol
Synonyms	Glycyl-prolyl-glycine; GLY-PRO-GLY; Gly-Pro-Gly-OH; H-Gly-Pro-Gly; Glycyl-L-prolylglycine; L-Glycyl-L-prolylglycine; Tripeptide G-P-G; 2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]acetic acid
EINECS	Contact for details

Quality Control

Our H-Gly-Pro-Gly-OH is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results for purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.