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n-Propyllithium CAS NO 2417-93-8


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CAS No.:2417-93-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Propyllithium is a highly reactive organolithium compound, widely recognized as a powerful nucleophile and base in synthetic organic chemistry. Its primary value lies in its ability to efficiently introduce the propyl group into molecular frameworks, enabling the synthesis of complex intermediates and fine chemicals. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise carbon-chain elongation is required.

Application

  • Pharmaceutical Intermediate Synthesis: A key reagent for the alkylation of carbonyl compounds, esters, and epoxides to build active pharmaceutical ingredients (APIs).
  • Polymer & Material Science: Used as an initiator for anionic polymerization to produce specialized polymers with controlled architectures.
  • Agrochemical Manufacturing: Employed in the synthesis of herbicides, fungicides, and other crop protection agents requiring propyl-substituted structures.
  • Fine Chemical Production: Facilitates the preparation of complex organic molecules, including flavors, fragrances, and liquid crystals.
  • Lithiation Reactions: Acts as a strong base for deprotonation and metal-halogen exchange reactions to generate other organometallic species.
  • Research & Development: A fundamental tool in academic and industrial R&D labs for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name n-Propyllithium
CAS No. 2417-93-8
Molecular Formula C3H7Li
Molecular Weight 50.00 g/mol
Synonyms Lithium Propyl; Propyl Lithium; Propyllithium; 1-Propyllithium; n-PrLi; Propane, 1-lithio-; Lithium n-propyl
EINECS 219-329-8

Quality Control

Our n-Propyllithium is manufactured under stringent quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot is rigorously tested to confirm identity, purity, and concentration, typically supplied as a solution in a specified hydrocarbon solvent. A comprehensive Certificate of Analysis (COA) detailing assay results, solvent content, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its pyrophoric and moisture-sensitive nature, this material must be stored and handled under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area, away from oxidizing agents and sources of ignition. For specific storage temperature recommendations based on the supplied solvent concentration, please refer to the Safety Data Sheet.

Specification

Item Specification
Appearance Clear, colorless to slightly yellow solution
Identification (IR) Conforms
Assay (Titration) Typically 1.0-2.0 M in specified solvent (e.g., cyclohexane, hexanes)
Purity (by NMR) ≥ 95% (relative)
Solvent Content Balance
Acidity (by Titration) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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