Description

3-Bromopropionitrile is a versatile bifunctional organic building block, containing both a reactive bromine atom and a nitrile group. This compound is essential for synthetic chemists as it facilitates efficient carbon-chain elongation and the introduction of functional groups in a single step. It is a key intermediate for the synthesis of pharmaceuticals, agrochemicals, and advanced materials, valued for its role in nucleophilic substitution and cyclization reactions.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyanoethyl or propionitrile moieties.
• Agrochemical Synthesis: Serves as a precursor for herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the production of polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A valuable reagent for organic synthesis, including Michael additions and the preparation of heterocyclic compounds.
• Ligand and Catalyst Preparation: Used to synthesize specialized phosphine or amine ligands for catalytic processes.
• Cross-coupling Reactions: Acts as an electrophile in palladium-catalyzed reactions for carbon-carbon bond formation.

Basic Information

Product Name	3-Bromopropionitrile
CAS No.	2417-90-5
Molecular Formula	C3H4BrN
Molecular Weight	133.97 g/mol
Synonyms	β-Bromopropionitrile; 3-Bromopropanenitrile; Bromoethyl cyanide; 2-Bromoethyl cyanide; β-Bromopropiononitrile; NSC 9376; 3-Brompropanonitril
EINECS	219-326-5

Quality Control

Our 3-Bromopropionitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including assay by GC/HPLC, identity confirmation (IR, NMR), and impurity profiling to ensure it meets the high standards required for industrial and research applications. A Certificate of Analysis (COA) detailing purity, physical properties, and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, keep the container tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.480 - 1.490
Density (20°C)	1.60 - 1.65 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.