Description

Diethylstilbestrol Glucuronide is a major, water-soluble metabolite of the synthetic estrogen diethylstilbestrol (DES). This compound is of significant importance for research and analytical applications, particularly in the study of estrogen metabolism, pharmacokinetics, and toxicology. It serves as a critical reference standard for laboratories in the pharmaceutical, clinical diagnostics, and environmental monitoring sectors, enabling accurate quantification and method validation.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for the quality control and assay development of related pharmaceutical products.
• Metabolite Research: Essential for in vitro and in vivo studies investigating the metabolic pathways, bioavailability, and clearance of diethylstilbestrol.
• Clinical & Diagnostic Testing: Used to calibrate equipment and validate methods (e.g., LC-MS/MS, HPLC) for detecting DES and its metabolites in biological samples for toxicology and endocrinology studies.
• Veterinary Drug Residue Analysis: Acts as a key standard in testing protocols to monitor for illegal DES use in livestock and ensure food safety compliance.
• Environmental Monitoring: Applied in analytical methods to trace estrogenic compound pollution and study the environmental fate of synthetic hormones.
• Biochemical Reagent: Utilized in enzymatic studies, particularly those involving glucuronidation processes and phase II metabolism.

Basic Information

Product Name	Diethylstilbestrol Glucuronide
CAS No.	2408-40-4
Molecular Formula	C24H28O8
Molecular Weight	444.48 g/mol
Synonyms	DES Glucuronide; Diethylstilbestrol 4'-Glucuronide; Diethylstilbestrol Glucuronide Sodium Salt; Stilbestrol Glucuronide; 4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol glucuronide; NSC 112989; Glucuronide of Diethylstilbestrol; Diethylstilboestrol Glucuronide
EINECS	Contact for details

Quality Control

Our Diethylstilbestrol Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and analytical use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.