Description

Acetic Acid, [(Trifluoromethyl)Thio]- is a specialized organosulfur and organofluorine compound that serves as a versatile building block in advanced chemical synthesis. Its unique structure, featuring both a thioether linkage and a highly electronegative trifluoromethyl group, makes it a valuable reagent for introducing the SCF3 moiety into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. Its application is critical in creating compounds with enhanced metabolic stability, lipophilicity, and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethylthio group can improve biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or modifier in the development of specialty polymers and advanced materials with specific surface or electronic properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the preparation of novel ligands and catalysts used in cross-coupling and other catalytic reactions.
• Fluorine Chemistry Research: An essential reagent in academic and industrial R&D for exploring new methodologies in fluorine chemistry and the synthesis of complex fluorinated molecules.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	Acetic Acid, [(Trifluoromethyl)Thio]-
CAS No.	2408-17-5
Molecular Formula	C3H3F3O2S
Molecular Weight	160.11 g/mol
Synonyms	2-[(Trifluoromethyl)thio]acetic Acid; (Trifluoromethylthio)acetic Acid; Acetic Acid, (Trifluoromethylthio)-; TFMTA; S-Trifluoromethyl Thioglycolic Acid; α-[(Trifluoromethyl)thio]acetic Acid; 2-(Trifluoromethylsulfanyl)acetic Acid; NSC 92486
EINECS	Contact for details

Quality Control

Our Acetic Acid, [(Trifluoromethyl)Thio]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.