Description

Acetamide, 2,2,2-Trifluoro-n-[2-(Trifluoromethyl)Phenyl]- is a specialized fluorinated acetamide derivative characterized by its unique trifluoromethyl-substituted aromatic and amide structure. This compound matters for its role as a high-value pharmaceutical intermediate and agrochemical building block, where its fluorine atoms impart enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by R&D and production teams in the fine chemical, crop protection, and advanced material synthesis sectors.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a critical precursor for advanced herbicides and fungicides, leveraging the trifluoromethyl groups to improve biological activity and environmental persistence.
• Liquid Crystal & OLED Material Research: Used in the synthesis of fluorinated organic compounds for electronic display technologies and organic light-emitting diodes (OLEDs).
• Fluorinated Polymer Modification: Acts as a monomer or modifier to introduce specific fluorinated side chains, enhancing polymer properties like chemical resistance and thermal stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a protecting group or directing agent in complex multi-step synthetic routes.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-[2-(Trifluoromethyl)Phenyl]-
CAS No.	2368-64-1
Molecular Formula	C10H7F6NO
Molecular Weight	271.16 g/mol
Synonyms	N-[2-(Trifluoromethyl)phenyl]-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[2-(trifluoromethyl)phenyl]acetamide; α,α,α-Trifluoro-N-[2-(trifluoromethyl)phenyl]acetamide; 2-(Trifluoromethyl)phenyltrifluoroacetamide; TFMPTA; TFA-2-TFMPA; CAS 2368-64-1
EINECS	Contact for details

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-[2-(Trifluoromethyl)Phenyl]- is manufactured under a cGMP-compliant quality management system to ensure batch-to-batch consistency and traceability. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy for rigorous identity confirmation and purity verification. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.