Description

1,2,3,5-Tetrafluorobenzene is a versatile fluorinated aromatic compound, valued for its role as a key building block in advanced chemical synthesis. Its unique substitution pattern makes it an essential intermediate for creating complex molecules with tailored properties. This high-purity material is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and fungicides, where fluorine introduction improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a fundamental building block for fluorine-containing components in electronic display materials and organic light-emitting diodes.
• Polymer & Resin Modification: Employed to incorporate fluorine into polymer backbones, enhancing chemical resistance, thermal stability, and surface properties of high-performance plastics and coatings.
• Organic Synthesis & Catalysis: A valuable reagent in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in organometallic chemistry.
• Refrigerant & Propellant Research: Investigated as a potential component or intermediate in next-generation, low-global-warming-potential (GWP) fluorocarbon blends.

Basic Information

Product Name	1,2,3,5-Tetrafluorobenzene
CAS No.	2367-82-0
Molecular Formula	C6H2F4
Molecular Weight	150.07 g/mol
Synonyms	1,2,3,5-Tetrafluorobenzene; Benzene, 1,2,3,5-tetrafluoro-; NSC 9235; Tetrafluorobenzene (1,2,3,5-); 1,2,3,5-Tetrafluorobenzol; UNII-9F8W8K1B4V; 1,2,3,5-Tetrakis(fluoranyl)benzene
EINECS	219-132-7

Quality Control

Our 1,2,3,5-Tetrafluorobenzene is manufactured under stringent quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Density (20°C)	~1.50 g/mL
Boiling Point	~115-117°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.