Description

1,3-Dichloro-2,5-difluorobenzene is a high-purity, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for the development of complex molecules, particularly in the agrochemical and pharmaceutical sectors. This compound is essential for researchers and manufacturers seeking to introduce specific halogen functionalities into target structures, enabling the fine-tuning of biological activity and physical properties.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms contribute to enhanced efficacy and environmental profile.
• Pharmaceutical Building Block: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing complex aromatic cores in drug candidates.
• Liquid Crystal & Electronic Chemicals: Serves as a starting material for the synthesis of fluorinated liquid crystals and other specialty electronic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create novel aromatic compounds.
• Polymer Modification: Acts as a monomer or modifier in the production of specialty polymers, including high-performance resins and engineering plastics.

Basic Information

Product Name	1,3-Dichloro-2,5-difluorobenzene
CAS No.	2367-80-8
Molecular Formula	C6H2Cl2F2
Molecular Weight	182.98 g/mol
Synonyms	2,5-Difluoro-1,3-dichlorobenzene; 1,3-Dichloro-2,5-difluorobenzene; Benzene, 1,3-dichloro-2,5-difluoro-; 2,5-Difluoro-m-dichlorobenzene; m-Dichloro-2,5-difluorobenzene
EINECS	219-124-3

Quality Control

Our 1,3-Dichloro-2,5-difluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.