Description

4,4,4-Trifluorobutan-2-One is a versatile fluorinated ketone building block with the CAS number 2366-70-3. Its value lies in its unique trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, serving as a key intermediate in the synthesis of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for improved bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the introduction of fluorine atoms can enhance activity and environmental persistence.
• Organic Synthesis & Chemical Research: Serves as a versatile reagent for introducing the -COCF3 moiety in complex organic molecules, facilitating the development of new compounds in academic and industrial R&D.
• Material Science Precursor: Employed in the synthesis of specialty polymers and advanced materials that benefit from the unique electronic and physical properties of fluorine-containing groups.
• Liquid Crystal & Electronic Chemicals: Acts as a key intermediate in the manufacturing of fluorinated liquid crystals and other electronic materials used in display technologies.

Basic Information

Item	Details
Product Name	4,4,4-Trifluorobutan-2-One
CAS No.	2366-70-3
Molecular Formula	C4H5F3O
Molecular Weight	126.08 g/mol
Synonyms	1,1,1-Trifluoro-3-butanone; 3-Butanone, 1,1,1-trifluoro-; 4,4,4-Trifluoro-2-butanone; 4,4,4-Trifluorobutanone; 1,1,1-Trifluorobutan-3-one; Trifluoroethyl methyl ketone; Methyl trifluoroethyl ketone; 4,4,4-Trifluorobutan-2-on (German)
EINECS	219-124-6

Quality Control

Our 4,4,4-Trifluorobutan-2-One is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.