Description

3,3-Difluorobutanoic Acid is a versatile fluorinated carboxylic acid building block essential for advanced organic synthesis. Its value lies in the strategic introduction of fluorine atoms and a reactive carboxyl group, enabling the modification of molecular properties critical in modern chemical development. This compound is particularly sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for creating novel compounds with enhanced biological activity, stability, and performance.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs to improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where fluorine incorporation can enhance efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and device performance.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Reagent: A valuable reagent for preparing esters, amides, and acid chlorides used in further complex molecule construction.
• Fluorine Chemistry Research: Fundamental compound for academic and industrial research exploring new reactions and properties of organofluorine molecules.

Basic Information

Product Name	3,3-Difluorobutanoic Acid
CAS No.	2366-61-2
Molecular Formula	C4H6F2O2
Molecular Weight	124.09 g/mol
Synonyms	3,3-Difluorobutyric Acid; Butanoic acid, 3,3-difluoro-; 3,3-Difluorobutanoic acid; 3,3-Difluorobuttersäure (German); Acide 3,3-difluorobutanoïque (French); α,α-Difluorobutyric Acid; DFBA
EINECS	Contact for details

Quality Control

Our 3,3-Difluorobutanoic Acid is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the exacting requirements of research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizers, and sources of ignition. Due to its acidic nature, handle with appropriate personal protective equipment in a fume hood or with adequate ventilation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.390 - 1.400
Density (g/mL, 20°C)	1.25 - 1.35

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.