Description

Acetoacetic Acid, 2,4,4-Trifluoro- (8Ci) is a specialized fluorinated derivative of acetoacetic acid, serving as a high-value building block in advanced organic synthesis. Its unique trifluoromethyl and fluorine substituents impart distinct electronic and steric properties, making it a critical intermediate for creating complex molecules with enhanced stability and bioactivity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and fungicides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or precursor for specialty polymers and coatings with unique chemical resistance and surface properties.
• Liquid Crystal & OLED Materials: A valuable intermediate for creating fluorinated components used in electronic display technologies.
• Organic Synthesis & Catalysis: Employed in research for constructing complex heterocycles and as a ligand precursor in catalytic systems.
• Fluorine Chemistry Research: A crucial reagent for studying the effects of fluorine substitution on molecular reactivity and physical properties.

Basic Information

Product Name	Acetoacetic Acid, 2,4,4-Trifluoro- (8Ci)
CAS No.	2365-96-0
Molecular Formula	C4H3F3O3
Molecular Weight	156.06 g/mol
Synonyms	2,4,4-Trifluoroacetoacetic Acid; 4,4,4-Trifluoro-3-oxobutanoic Acid; 3-Oxo-4,4,4-trifluorobutanoic Acid; 4,4,4-Trifluoroacetoacetate (acid form); TFAA (context-specific); Trifluoromethyl acetoacetic acid; Butanoic acid, 3-oxo-4,4,4-trifluoro-; NSC 163022
EINECS	Contact for details

Quality Control

Every batch of 2,4,4-Trifluoroacetoacetic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, supporting compliance with cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.