Description

3-Chloro-n-(4-Methoxy-Benzyl)-Propionamide CAS NO 2364-76-3 is a specialized organic intermediate featuring a chloroalkyl amide structure linked to a methoxy-substituted benzyl group. This molecular architecture makes it a valuable building block for the synthesis of more complex chemical entities, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, agrochemicals, and advanced material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting neurological or inflammatory pathways.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed reactions or as a component in organocatalysts.
• Peptidomimetic Research: The amide and chloroalkyl functionalities make it suitable for constructing peptidomimetic scaffolds in bioorganic chemistry.
• Material Science Precursor: Potential monomer or cross-linking agent in the development of specialty polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function or cellular processes.

Basic Information

Product Name	3-Chloro-n-(4-Methoxy-Benzyl)-Propionamide
CAS No.	2364-76-3
Molecular Formula	C11H14ClNO2
Molecular Weight	227.69 g/mol
Synonyms	N-(4-Methoxybenzyl)-3-chloropropionamide; 3-Chloro-N-[(4-methoxyphenyl)methyl]propanamide; 3-Chloropropionyl-4-methoxybenzylamine; 1-(4-Methoxybenzylamino)-3-chloropropan-1-one; p-Methoxybenzyl 3-chloropropionamide; 2364-76-3; 3-Chloro-N-(4-methoxybenzyl)propanamide
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-n-(4-Methoxy-Benzyl)-Propionamide undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development as well as scale-up production. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or GC), identity confirmation (by IR, NMR), and impurity profiles is provided with each shipment to guarantee reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.