Description

Mtt (CAS NO 2348-71-2) is a vital biochemical reagent widely used in cell biology and pharmaceutical research. Its primary value lies in its role as a key component in colorimetric assays for measuring cell proliferation, viability, and cytotoxicity. This compound is essential for researchers and quality control laboratories in the biotechnology, pharmaceutical, and academic sectors who require reliable and sensitive assay tools.

Application

• Cell Proliferation and Viability Assays: A critical reagent in the MTT assay for quantifying metabolic activity of living cells.
• Drug Screening and Cytotoxicity Testing: Used in high-throughput screening to evaluate the effects of novel drug candidates on cell health.
• Cancer Research: Employed to assess the sensitivity of cancer cell lines to chemotherapeutic agents and radiation.
• Immunology Studies: Utilized to measure lymphocyte activation and immune cell responses in vitro.
• Toxicology and Safety Assessment: Applied in environmental and industrial toxicology to determine the cytotoxic potential of chemicals.
• Biomaterial and Implant Testing: Helps evaluate the biocompatibility of new materials by assessing their impact on surrounding cells.

Basic Information

Product Name	Mtt
CAS No.	2348-71-2
Molecular Formula	C18H16BrN5S
Molecular Weight	414.32 g/mol
Synonyms	Thiazolyl Blue Tetrazolium Bromide; MTT Tetrazolium; 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; MTT Reagent; MTT Salt; Tetrazolium Salt Yellow; MTT Formazan Precursor; Cell Proliferation Kit I (MTT) Component
EINECS	Contact for details

Quality Control

Our Mtt is produced under strict quality management protocols to ensure batch-to-batch consistency and high performance in sensitive assays. Each lot undergoes comprehensive analytical testing, including purity verification by HPLC and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and performance.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in water
Biological Activity	Passes cell-based assay performance test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.