Description

Thioproperazine Dimesylate is a high-purity pharmaceutical intermediate and research chemical. This compound is critical for the development and synthesis of advanced therapeutic agents, particularly in the field of neuropharmacology. It is primarily utilized by pharmaceutical manufacturers, research institutions, and contract development organizations engaged in the development of central nervous system (CNS) active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of antipsychotic and neuroleptic active pharmaceutical ingredients (APIs).
• Research & Development: Used in preclinical and pharmacological studies to investigate dopaminergic and serotonergic receptor interactions.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Chemical Synthesis: Employed in organic synthesis for the preparation of novel chemical entities with potential therapeutic value.
• Biochemical Research: Utilized in *in vitro* assays to study cellular mechanisms and signal transduction pathways related to neurological function.

Basic Information

Item	Detail
Product Name	Thiopperazine Dimesylate
CAS No.	2347-80-0
Molecular Formula	C22H30N4O6S3
Molecular Weight	566.70 g/mol
Synonyms	Thioproperazine Dimethanesulfonate; Thioproperazine Methanesulfonate; TPS; 10-[3-(4-Methylpiperazin-1-yl)propyl]-2-(methylsulfanyl)-10H-phenothiazine Dimethanesulfonate; 2-Methylmercapto-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine Dimethanesulfonate; Majeptil (brand name derivative); Vontril
EINECS	Contact for details

Quality Control

Our Thioproperazine Dimesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.