Description

2-Amino-5-Fluoroacetophenone is a versatile fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its value lies in the strategic combination of an amino group and a fluorine atom on the acetophenone core, enabling precise molecular modifications. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in fluorination chemistry and palladium-catalyzed cross-coupling reactions.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized fluorinated dyes and functional chromophores.

Basic Information

Product Name	2-Amino-5-Fluoroacetophenone
CAS No.	2343-25-1
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	1-(2-Amino-5-fluorophenyl)ethanone; 2-Acetylamino-5-fluorobenzene; 5-Fluoro-2-aminoacetophenone; 2-Amino-5-fluoro-1-phenylethanone; 2-Amino-5'-fluoroacetophenone; 2-Acetamido-5-fluorobenzene; 2-Amino-5-fluorophenyl methyl ketone
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Fluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.