Description

5-Fluoro-2,3-Dihydro-1H-Inden-2-Amine is a versatile and high-purity fluorinated indane derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique amine-functionalized, fluorine-substituted bicyclic structure, which is essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of central nervous system (CNS) agents, enzyme inhibitors, and other therapeutic candidates.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides, where the fluorine atom enhances bioavailability and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers or advanced organic materials with tailored electronic properties.
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes to study biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules at various scales.

Basic Information

Product Name	5-Fluoro-2,3-Dihydro-1H-Inden-2-Amine
CAS No.	2340-06-9
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	5-Fluoro-2-aminoindane; 2-Amino-5-fluoroindane; 5-Fluoroindan-2-amine; 5-Fluoro-2,3-dihydro-1H-inden-2-amine; 2,3-Dihydro-5-fluoro-1H-inden-2-amine; 2340-06-9; 5-Fluoro-2-indanamine
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-2,3-Dihydro-1H-Inden-2-Amine is produced under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.