Description

2,3,5,6-Tetrafluoroanisole is a fluorinated aromatic ether compound of significant interest in advanced chemical synthesis. Its unique structure, featuring four fluorine atoms, makes it a valuable building block for introducing lipophilicity and metabolic stability into target molecules. This high-purity intermediate is primarily sought by the pharmaceutical and agrochemical industries for the research and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Organic Electronics: Employed in the development of electron-transport materials and semiconductors for OLEDs and organic photovoltaics.
• Advanced Polymer Modification: Acts as a monomer or modifier to create specialty fluoropolymers with enhanced chemical resistance and low surface energy.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and creating novel fluorinated aromatic compounds in academic and industrial R&D labs.

Basic Information

Product Name	2,3,5,6-Tetrafluoroanisole
CAS No.	2324-98-3
Molecular Formula	C7H4F4O
Molecular Weight	180.10 g/mol
Synonyms	1,2,4,5-Tetrafluoro-3-methoxybenzene; Methoxy-2,3,5,6-tetrafluorobenzene; 2,3,5,6-Tetrafluorophenyl methyl ether; Anisole, 2,3,5,6-tetrafluoro-; Benzene, 1,2,4,5-tetrafluoro-3-methoxy-; 3-Methoxy-1,2,4,5-tetrafluorobenzene
EINECS	219-045-4

Quality Control

Our 2,3,5,6-Tetrafluoroanisole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, guaranteeing consistent quality and reliable supply for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.430
Density (20°C)	1.45 - 1.55 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.