Description

Lucigenin is a high-purity, synthetic heterocyclic compound widely recognized as a highly efficient chemiluminescent probe. Its core value lies in its exceptional ability to generate a strong, measurable light signal upon reaction with reactive oxygen species, particularly superoxide anion. This property makes it indispensable for researchers and quality control professionals in life sciences and industrial chemistry who require sensitive detection and quantification methods. Key industries that rely on this compound include pharmaceutical R&D, biochemical assay development, and environmental monitoring for oxidative stress.

Application

• Chemiluminescence-Based Assays: Primary application for the sensitive detection and quantification of superoxide anion (O₂⁻) and other reactive oxygen species (ROS) in biological samples.
• Pharmaceutical Research: Used in high-throughput screening (HTS) to study oxidative stress, evaluate drug efficacy, and investigate mechanisms of action related to free radical biology.
• Biochemical Research: Serves as a critical tool in enzymology for studying the activity of oxidases, such as NADPH oxidase, and in cellular signaling pathway analysis.
• Environmental & Food Science: Employed in assays to monitor antioxidant capacity, assess pro-oxidant contaminants, and evaluate oxidative stability in products.
• Clinical Diagnostics Development: Utilized in the development of diagnostic kits and sensors for conditions involving oxidative stress, including inflammation and neurodegenerative diseases.
• Material Science: Applied in the study of catalytic processes and the development of novel chemiluminescent materials and sensors.

Basic Information

Product Name	Lucigenin
CAS No.	2315-97-1
Molecular Formula	C₂₈H₂₂N₄O₆
Molecular Weight	510.50 g/mol
Synonyms	Bis-N-methylacridinium nitrate; 10,10'-Dimethyl-9,9'-biacridinium dinitrate; N,N'-Dimethyl-9,9'-biacridinium dinitrate; Lucigenin; DMBAn; L-6868; L-6882; L-012
EINECS	219-025-1

Quality Control

Our Lucigenin is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results. We support compliance with various research and development standards, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent absorption of water vapor. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Chemiluminescence Activity	Passes performance test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.