Description

3'-Trifluoromethylpropionanilide is a specialized fluorinated organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of the trifluoromethyl group is crucial for modulating biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate this valuable fluorinated motif into their target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances lipophilicity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated into specialty polymers to impart unique properties such as chemical resistance, thermal stability, and low surface energy.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination pathways in academic and industrial R&D laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	3'-Trifluoromethylpropionanilide
CAS No.	2300-88-1
Molecular Formula	C10H10F3NO
Molecular Weight	217.19 g/mol
Synonyms	N-(3-(Trifluoromethyl)phenyl)propionamide; 3'-(Trifluoromethyl)propionanilide; Propionanilide, 3'-trifluoromethyl-; 3-(Trifluoromethyl)phenylpropionamide; α,α,α-Trifluoro-m-propionotoluidide; m-Trifluoromethylpropionanilide; 1-Propanamide, N-[3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 3'-Trifluoromethylpropionanilide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure consistent quality and reliable performance in your synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.