Description

Ethyl (2E)-2-Cyano-3-(4-Nitrophenyl)-2-Propenoate is a high-purity, light-sensitive organic intermediate characterized by its conjugated cyanoacrylate structure with a nitroaryl substituent. This compound is valued for its role as a versatile building block in the synthesis of complex molecules, particularly in pharmaceutical and advanced material research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing pharmacophores and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing nitrophenyl and cyanoacrylate motifs for potential therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its electron-withdrawing groups to modulate biological activity.
• Organic Electronic Materials: Serves as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and photovoltaics due to its electron-accepting properties.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized dyes and pigments where the nitro and cyano groups contribute to color and stability.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for creating complex biaryl structures.
• Academic and Industrial R&D: Employed in methodological studies and as a standard in analytical chemistry for developing new synthetic routes.

Basic Information

Product Name	Ethyl (2E)-2-Cyano-3-(4-Nitrophenyl)-2-Propenoate
CAS No.	2286-33-1
Molecular Formula	C₁₂H₁₀N₂O₄
Molecular Weight	246.22 g/mol
Synonyms	(2E)-2-Cyano-3-(4-nitrophenyl)-2-propenoic acid ethyl ester; Ethyl (E)-2-cyano-3-(4-nitrophenyl)acrylate; Ethyl 2-cyano-3-(4-nitrophenyl)-2-propenoate; 4-Nitrophenylcyanocinnamic acid ethyl ester; (E)-Ethyl 2-cyano-3-(4-nitrophenyl)acrylate; 2-Propenoic acid, 2-cyano-3-(4-nitrophenyl)-, ethyl ester, (2E)-; Ethyl α-cyano-4-nitrocinamate
EINECS	Contact for details

Quality Control

Our Ethyl (2E)-2-Cyano-3-(4-Nitrophenyl)-2-Propenoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment ensures the material is suitable for demanding applications in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.