Description

1,3-Dichloro-2-Fluorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers engaged in creating active ingredients, specialty chemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a specific halogenated benzene core.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes.
• Polymer Modification: Employed to introduce halogenated aromatic units into polymer chains, altering thermal and chemical resistance properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to create biaryl and other complex structures.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating novel fluorinated compounds in R&D laboratories.

Basic Information

Product Name	1,3-Dichloro-2-Fluorobenzene
CAS No.	2268-05-5
Molecular Formula	C6H3Cl2F
Molecular Weight	164.99 g/mol
Synonyms	2-Fluoro-1,3-dichlorobenzene; 1,3-Dichloro-2-fluorobenzene; 2,6-Dichlorofluorobenzene; 2-Fluoro-m-dichlorobenzene; m-Dichloro-o-fluorobenzene; Benzene, 1,3-dichloro-2-fluoro-; NSC 92438
EINECS	218-880-1

Quality Control

Our 1,3-Dichloro-2-Fluorobenzene is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and metals. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.48 g/mL
Boiling Point	~185-188°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.