Description

Didemethylchlorpromazine Sulfoxide is a key pharmaceutical intermediate and reference standard of significant interest in research and development. Its primary value lies in its role as a metabolite and synthetic precursor in the study of phenothiazine-derived compounds. This product is essential for pharmaceutical manufacturers, analytical laboratories, and research institutions engaged in drug metabolism studies, impurity profiling, and the synthesis of advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Critical for the synthesis and process development of phenothiazine-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Metabolite Studies: Serves as a key metabolite standard in pharmacokinetic and drug metabolism research for related neuroleptic agents.
• Impurity Profiling: Employed to identify, quantify, and control process-related impurities and degradation products in final drug substances.
• Research & Development: Utilized in academic and industrial R&D for exploring new chemical entities and biological pathways related to its parent compounds.

Basic Information

Product Name	Didemethylchlorpromazine Sulfoxide
CAS No.	2232-49-7
Molecular Formula	C17H19ClN2OS
Molecular Weight	334.86 g/mol
Synonyms	2-Chloro-10-[3-(methylamino)propyl]phenothiazine 5-oxide; Nor2-Chlorpromazine Sulfoxide; Desdimethylchlorpromazine Sulfoxide; 5-Oxido-2-chloro-10-(3-methylaminopropyl)phenothiazine; Chlorpromazine Sulfoxide Didemethylated; Nor1Nor2-Chlorpromazine Sulfoxide; NSC 108164; Didemethyl CPZ Sulfoxide
EINECS	Contact for details

Quality Control

Our Didemethylchlorpromazine Sulfoxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets high-grade specifications suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.